Build Acid Sharpshooter everywhere possible and a few smokehouses with 2 AIs following me. As soon as the cutscene appears to reveal the Blob-boss monster, the game freezes and shortly thereafter crashed to desktop.

Your on-site file upload does not let me proceed, so here is a mediafire Link with all requested files in a .zip Archive:

https://www.mediafire.com/file/p5yoq3nlxorst0u/ED2Crash.zip/file