If anybody will deside to help you, they will need your gamesave  and Diagnostics-xxxxxxxxx.html file. at least.

here is a save game : 

tour 90.sav

Here are the diagnostics : 

Diagnostics - 2020'10'22 @0104'27''.zip

If you need anything else, 

plz ask !

Regards

Found something interesting.  Apparently there is a pathing error in the trade route.  Manage to make everything work by switching subsidiaries  : 

Pic 1 : I avoid using Perseus and Hydrus as subsidiaries and everything works

Pic 2 : I have Perseus as a subsidiaries and there are no trade routes to it

Found out what was going on :

- Apparently if you have a close borders agreement with a faction then any subsidiaries on a direct route (aka not through a wormhole) will male that subsidiaries simply disapears like it never existed.  You could even get the 'no direct route, plz research wormhole tech' (even if you already did!) if all of your subsidiaries exists on a direct route from a close borders faction.

What is very confusing is that if, however you are going through that faction (that you have closed borders with) and going wormhole to wormhole then everything works fine !

Weird huh...