Almost everytime I try to start a new game I get an error that states "A Serious Error has Occured" there is no other information no error logs or anything just that notice. This happens in 98% of the games I try to start.

Have you tried any of the solutions presented in the Common Issues, Guides, and Solutions thread? If so, what were the results?

no none of the options in the common issues section works. this problem has been occuring since the vaulters DLC first dropped and to clarify i can open and run endless space 2 without issues i can even load older save files in game without any problems, its only when i try to start a new game that i get any problem. 

There aren't any diagnostics files or logs made whenever this occurs.  This even occurs when trying quick start it just goes through the load screen and then just drops out to the main menu with a notice saying "A Serious Error has Occured". I have also made sure that the games isnt being blocked or flagged by my protection programs.

Getting the same error as well, no output files made.

Perhaps try to start game with antivirus software deactivated (you can go offline before) to check out it's not the reason for crash?

Well not sure what changed but after updating to version 1.4.3 S5 GOLD the game seems to be functioning normal now. Was able to start up 4 seperate time without error. I'll be posting again if the problem resurfaces but for now it seems okay.