@baymax It could potentiall be that You have an old Registry.xml file in Your "Documents\Humankind\Users" Folder if You played earlier OpenDevs.
You can first drag and backup that file to Your desktop (in case You need it later) and then delete the copy of "Registry.xml" in the "Documents\Humankind\Users" Folder. Then try to reboot the game again. If the game works now, You can delete the old copy of that file on your desktop.
That Registry.xml is simply an xml file with alot of command lines of Your latest chosen settings in Humankind. Like resolution, fullscreen etc. If it is an old version, it can have settings that are incompatibkle with the latest version of Humankind.
I hope that helps Your issue.
Of course You do all that at Your own choice. Your PC. Your choice.
However it has helped both me and others to get the game to run. Of course Your issue could be something else. That is why it is good to save a backup of that file in case You need to put it back after if this solution doers not fix Your issue.
@baymax It can also be that Your anti-virus softwares firewall settings block the Humankind.exe from running. Then You need to "allow" it to run wathin the settings of Your anti-virus sofwares firewall settings.
You can first try simply to disable Your anti-virus software for a little while and try boot the game and see if it will start up properly. If it does then You know it's the anti-virus firewall that needs the setting changed to allow "Humankind.exe". I do not recommend You to run with the anti-virus deactivated for too long as that can leave You vulnerable to hackers and attacks.
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